ABSTRACT:

OBJECTIVE To show the postoperative clinical results, including the patient-reported time to return to the activities of daily living (ADLs), the radiographic aspects, and the grip strength of total joint arthroplasty in patients with stage-III rizarthrosis.
METHODS In the present single-center and prospective study, we analyzed total joint arthroplasty with an uncemented, metal-on-polyethylene prosthesis (Maia, Groupe Lepine). The inclusion criteria were patients with stage-III carpometacarpal (CMC) joint osteoarthritis, aged > 60 years, initially treated through non-surgical procedures. The exclusion criteria were patients presenting mental illness, alcohol abuse, rheumatological arthritis.
RESULTS During the study period (from January 2018-October 2023), 34 patients met the patient selection criteria. Three eligible patients received a different implant, and two were simultaneously submitted to surgery in another joint (metacarpophalangeal joint with Z- deformity); these subjects were not included in the study. After 25.1 months of the surgery, grip strength was of 87.75% regarding the opposite side, the scores on the Visual Analogue Scale (VAS) and on the short form of the Disabilities of the Arm, Shoulder, and Hand (QuickDASH) questionnaire were of 1, and the range of motion was of 81% compared to the unaffected side. On the X-ray examination, initial metacarpal subsidence was observed in 100% of the patients. Complications were observed in 2 (6.9%) patients
CONCLUSION The choice of total joint arthroplasty to treat active patients aged > 60 years with stage-III CMC joint arthritis preserves independence to perform ADLs and improves quality of life in the first 12 months of the procedure.

Keywords:
arthroplasty; carpometacarpal joints; osteoarthritis; thumb; trapezium bone.

RESUMO:

OBJETIVO Mostrar os resultados clínicos pós-operatórios, incluindo o tempo de retorno às atividades da vida diária (AVDs) relatado pelo paciente, os aspectos radiográficos e a força de preensão, da artroplastia total em pacientes com rizartrose em estágio III.
MÉTODOS Neste estudo prospectivo e unicêntrico, analisou-se a artroplastia total com prótese não cimentada de metal-polietileno (Maia, Groupe Lepine). Os critérios de inclusão foram pacientes com osteoartrite da articulação carpometacarpal (CMC) em estágio III, idade acima de 60 anos, tratados inicialmente com procedimentos não cirúrgicos. Os critérios de exclusão foram pacientes com doenças mentais, abuso de álcool e artrite reumatológica.
RESULTADOS Durante o estudo (de janeiro de 2018 a outubro de 2023), 34 pacientes atenderam aos critérios de seleção. Três pacientes elegíveis receberam outro implante, e dois foram simultaneamente submetidos a cirurgia em outra articulação (metacarpofalangiana com deformidade em Z); estes indivíduos não foram incluídos no estudo. Após 25,1 meses da cirurgia, a força de preensão era de 87,75% em relação ao lado oposto, as pontuações na Escala Visual Analógica (EVA) e na versão curta do questionário de Incapacidade do Braço, Ombro e Mão (Quick Disabilities of the Arm, Shoulder and Hand, QuickDASH) eram de 1, e a amplitude de movimento era de 81% em comparação ao lado não acometido. No exame radiográfico, observou-se subsidência inicial do metacarpo em 100% dos pacientes. Dois pacientes (6,9%) apresentaram complicações.
CONCLUSÃO A escolha da artroplastia total para o tratamento de pacientes ativos com mais de 60 anos e artrite da articulação CMC em estágio III preserva a independência para a realização de AVDs e melhora a qualidade de vida nos primeiros 12 meses após o procedimento.

Palavras-chave:
articulações carpometacarpais; artroplastia; osteoartrite; polegar; trapézio.

FIGURES

Citation: Aita MA, Aita GC, Rocha C, Savaris S, Leite M, Cabanilla SP. Arthroplasty in Thumb (CMC Joint) Osteoarthritis: Avoiding Trapeziectomy. 60(05):. doi:10.1055/s-0045-1812997
Note: Work developed at the Division of Orthopedics, Surgery Department, Faculdade de Medicina do ABC, Santo André, SP, Brazil.
Financial Support The authors declare that they did not received financial support from agencies in the public, private, or non-profit sectors to conduct the present study.

Conflict of Interests

The authors have no conflict of interests to declare.

Received: October 19 2024; Accepted: April 26 2025
 

INTRODUCTION

The prevalence of thumb basal joint arthritis increases with age and affects the ability to perform daily life activities (DLAs).1 The number of patients seeking treatment for this condition is likely to increase.2 However, there is no consensus regarding the prevention of total trapeziectomy in stage- III arthritis, according to the Eaton classification III.

There is doubt regarding the increase in complications and costs due to the complexity of the surgery.2 Total joint arthroplasty (TJA) in trapeziometacarpal joint osteoarthritis can be a safe procedure in patients older than 60 years of age and in stage III after failure of the first non-surgical treatment.3-6

In these cases, TJA is convenient; it does not hinder the performance of other techniques in case of failure, and it is a reproducible method that avoids stiffness, preserves the length of the thumb, increases the initial range of motion (RoM), enables a faster recovery, and it is an alternative to total trapeziectomy.7

The objective of the present study was to present the postoperative clinical outcomes of ATJ,2 including patientreported time to return to DLAs, radiographic features and hand grip strength, in patients with stage-III rhizarthrosis.

 

INCREASED COST

The need for an implant (Maia prosthesis, Groupe Lepine) increases the cost of the treatment and makes health insurers reluctant to provide coverage to the patients, despite the growing evidence of its benefits.

 

METHODS

The current research followed the ethical standards and was approved by the institutional Ethics Committee on Human Experimentation. An informed consent form was provided to all research participants, who read and signed it according to their will.

In the present single-center prospective study, we analyzed TJA with an uncemented metal-on-polyethylene prosthesis (Maia, Groupe Lepine). The institutional Ethics in Research committee approved the free and informed consent form, which the patients signed before being included in the study. The inclusion criteria were patients with stage-III carpometacarpal (CMC) joint osteoarthritis, aged > 60 years, initially treated through non-surgical procedures. The exclusion criteria were patients presenting mental illness, alcohol abuse, and rheumatological arthritis.

During the study period (from January 2018 to December 2023), 34 patients met the selection criteria. Three eligible patients received a different implant, and two were simultaneously submitted to surgery in another joint (metacarpophalangeal joint with Z-deformity); these subjects were not included in the study.

Post-hoc Analysis

The post-hoc analysis showed that 29 of the patients included did not show differences regarding age, sex, or CMC joint arthritis stage, with a statistical power of 85% according to a two-sided test and level of significance of 5%.8,9 The sample was composed of 25 women and 4 men with a mean ageof 64 (range: 60-74) years. Rhizarthrosis was classified according to the Eaton classification.10 Follow up period was 25.1 [12-66] months.

Surgical Technique

The goal of the treatment is to improve the balance between the mobility and stability of the CMC joint. Total joint arthroplasty must be perfectly positioned/fixated to enable osteointegration.7

The dorsal approach was chosen (►Fig. 1). The first step was to remove the joint surface of the base of the thumb, including the volar and medial beak osteophytes. Next, we prepared the medullary canal of the metacarpal with specific maneuver drills of increasing size until achieving press-fit stability and proper stem alignment along the metacarpal axis. The final implant was inserted, flush with the metacarpal base (►Fig. 2). Subsequently, we performed the cup placement in the trapezium taking care to avoid mechanical fixation of the cementless cup with the central subchondral bone and distal articular surface of the trapezium. The cup must be perfectly centered in the trapezium and in the center of motion of the CMC joint. To pass guide wire into trapezium center and the best direction that guide wire is 30° radially between the longitudinal axis of the diaphyses of the first and second metacarpals (coronal plane) and the anterior axis (sagittal plane), aided by fluoroscopy (►Figs. 3-4). Partial resection of the joint capsule was performed, with removal of free bodies and preservation of the palmar ligaments. A balance between soft tissues and implants is necessary to improve stabilization and avoid stiffness. The length of the thumb CMC joint can be assessed by comparing the length of the first and second rays before and after implanting the components. This can also be assessed by fluoroscopy, with analysis of the congruence of the first metacarpal arch on anteroposterior views with the thumb in 45° abduction, such as the “gothic arc” (►Fig. 5).

Total joint arthroplasty allows the restoration of the length (►Video 1), tendon balance, stabilization of the CMC joint and increases the best range of motion of the thumb.7

Video 1

Thumb dynamic fluoroscopy: total joint arthroplasty enables the restoration of the length of the thumb and of tendon balance, the stabilization of the base of the thumb, and the increase in thumb abduction. Online content including video sequences viewable at: https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0045-1812997.

Postoperative Care

A long thumb thumb splint was applied at the end of surgery and maintained for two weeks postoperatively. Skinsutures were removed so that the patient could actively move the thumb. A removable short thumb plaster cast was placed to be worn at nighttime and during DLAs. Pinching movement should be encouraged after 3 weeks, after which patients have no further restrictions.

All patients were assessed radiographic and clinically at 6 weeks, and again at 6 and 12 months after the procedure.11 Range of motion (RoM) was evaluated with a single tool (goniometer). Grip strength was measured with a specific Jamar hand dynamometer (Sammons Preston, Bolingbrook, IL) and value obtained was expressed as a percentage of that presented on the opposite side.12,13These values were classified into 4 groups according to the grip strength quartiles to in relation to the time of return to DLAs.14

The clinical outcomes were assessed using the Visual Analog Scale (VAS) for pain (range: 1-10, according to which 1 indicates no pain). Quality of life was determined by the Disabilities of the Arm, Shoulder and Hand (QuickDASH) questionnaire (range: 0-100, according to which 1 indicates the best result).15,16 The rate of complications was assessed 6 weeks, and again at 6 and 12 months after the procedure.

Radiographic Parameters

The main parameters were dorsal subluxation, implants aspect, and metacarpal subsidence (to maintain the trapezium-metacarpal joint space),whichwereevaluatedat 6 weeks, and 6 and 12 months after the surgery.

Statistical Methods

Table 1 shows the baseline demographics and the details of the injuries of the sample. The data were presented as mean or median according to the type of variable and its distribution. The objective and patient-reported outcomes are presented in ►Table 2. The mean VAS and QuickDASH scores were of 1 point. The RoM was 81% compared with the nonaffected side. Radiographic examination to preserve the initial parameters (implants without dislocation and without failure) showed metacarpal subsidence in 100% of patients. Complications were observed in 2 (6.9%) patients. These included trapezium fracture during surgery, which was treated with K-wire fixation and bone consolidation. Another patient presented pain and decreased thumb abduction and was treated with rehabilitation exercises, but maintained VAS = 3.

Table 1. Demographics of the sample, side of the lesions, and associated diseases
Identification Age (years) Profession Side Sex Associated diseases
1 69 Cook Right Female -
2 63 Secretary Right Female -
3 64 Designer Right Female -
4 63 Designer Left Female -
5 61 Secretary Left Female -
6 60 Teacher Left Female -
7 63 Teacher Right Female -
8 60 Businesswoman Right Female -
9 66 Accountant Left Female -
10 62 Secretary Left Female -
11 66 Nurse Left Female -
12 60 Saleswoman Right Female CTS
13 63 Dressmaker Right Female -
14 70 Judge Left Female -
15 64 Businesswoman Left Female CTS
16 67 Maid Right Female -
17 62 Maid Right Female De Quervain tenosynovitis
18 63 Cook Right Female -
19 67 Accountant Right Female -
20 70 Judge Right Male De Quervain tenosynovitis
21 64 Pastry chef Right Female -
22 60 Driver Right Male -
23 62 Seller Right Female Ganglion
24 60 Businesswoman Left Female -
25 70 Judge Left Male CTS
26 64 Maid Left Female De Quervain tenosynovitis
27 63 Designer Left Female DIP arthritis
28 66 Maid Right Female CTS
29 62 Businessman Right Male -
Table 2. Objective and patient-reported outcomes
Identification Follow-up (months) RoM (% opposite side) at 12 months Quick DASHscore VASscore Grip strength(% opposite side) |Return to ADLs (months) Complications
1 39 81 1 1 96 1 -
2 40 90 1 1 97 2 -
3 34 84 1 1 94 1 -
4 34 88 1 1 96 1 -
5 31 91 1 1 94 2 -
6 31 90 1 1 94 2 -
7 29 82 1 1 98 1 -
8 29 78 1 1 97 2 -
9 20 82 1 1 99 1 -
10 66 88 1 2 83 5 Trapezium fracture
11 76 91 1 1 91 1 -
12 36 80 1 1 96 1 -
13 14 78 1 1 92 1 -
14 12 74 1 1 94 2 -
15 17 79 1 1 96 1 -
16 16 82 1 1 98 1 -
17 18 83 1 1 87 2 -
18 19 91 1 1 98 2 -
19 14 90 1 2 96 1 -
20 14 90 1 1 96 1 -
21 14 82 5 3 87 6 -
22 24 88 1 1 96 1 -
23 21 73 1 1 91 1 -
24 20 89 1 2 83 1 -
25 12 70 11 2 82 5 Pain
26 12 64 1 1 81 1 -
27 12 63 1 1 96 2 -
28 12 66 1 1 92 1 -
29 12 62 1 1 97 1 -
Mean 25.10 81 1 1 87.75 2
 

DISCUSSION

In recent years, several studies have considered the outcomes of multiple total trapeziectomy techniques with suspensionplasty to be successful. However, recent studies1,2,11 have proven unsuccessful and suggested other procedures (which do not prevent other techniques from being performed in case of failure) to allow for faster recovery, with less pain and greater thumb strength, such as arthroscopy/ button suture or total arthroplasty..

Grip strength is a valid and reliable method used to evaluate objective outcomes and is an independent predictor of of patients’ inability to perform DLAs. Grip strength in the lower quartiles (first or second) increases the risk of inability to perform DLAs compared to strength in the higher quartiles (third or fourth).13,14In the present study, all patients showed values in the fourth quartile.

Bricout and Rezzouk17 reported a failure rate of 7.7% in the implementation of the MAIA prosthesis in a series of 156 patients. Maeda et al.11 showed a complications rate of 9.3%. We observed a lower incidence of complications (6.9%), and the clinical outcomes showed best RoM, shorter return time to DLAs, and a lower VAS than other studies.2,6,7

A criticism of the reduction in pain, complication, and costs of traditional total trapeziectomy is clear, but nowadays, it is not only about reducing pain but also maintaining grip strength, range of motion and functional capacity to perform ADLs is to maintain trapezialmetacarpal length and reducing the dorsal subluxation of the thumb metacarpal18 because increasing grip strength and it is appropriate to perform procedures that preserve the biomechanics of the thumb joint and, if it fails, we can perform another salvage procedure, such as preserving the trapezium by performing this prosthesis and, if this fails, a total trapeziectomy can be performed and thus we do not skip treatment steps. (“no burnt bridges” concept). Newton and Talwalkar,2 Duerinckx and Verstreken,7 and this study have demonstrated that TJA has certain advantages over other options, including stabilization and alignment of the CMC joint and preservation of the ability to perform DLAs and thumb length. Hustedt et al.8 showed that the time of return to work was 4.5 months in patients who had undergone total trapeziectomy. In our study, 93.1% of those who underwent the procedure returned to work within 2 months.

Farkash et al.19 reported a failure rate 11,32%, with these failed procedures in patients treated with partial arthroplasty of the CMC joint. The disadvantages of this method include costs, technical difficulty of the surgery, and the possible complication rate.

Currently, the concept “no burnt bridges” is accepted, and early definitive surgery in CMC joint arthritis, such as, total trapeziectomy, is controversial, because their exhausts surgical treatment options. This concept recommends the use of thumb arthroscopy or arthroplasty20,21 whenever possible. This approach improves the patients’ quality of life and reduces recovery time for DLAs and work-related activities. In addition, in case of failure, all surgical revision methods can be performed.

The present study is a prospective clinical trial, and all patients were operated on by a single hand surgeon, constituting a uniform group with complete follow-up. Nonetheless, some limitations need to be recognized. The present study is a case series and not a randomized clinical trial, the inclusion criterion was stage III according to the Eaton classification, and the sample size was small for QuickDASH, VAS, and grip strength analysis.

The increased cost is the main reason behind the difficulty in performing TJA. The method and implant for the treatment of thumb arthritis have evolved exponentially, generating excellent and are an option before comparative studies can consider them the gold standard and procedure of choice.21

 

CONCLUSION

The choice of TJA to treat active patients > 60 years old, with stage-III CMC joint arthritis, helps to preserve independence to perform DLAs and improve the patients’ life quality in the first 12 months after the procedure.

 

REFERENCES

Barrera J, Yao J. Arthroscopic Management of Thumb Carpometacarpal Joint Arthritis and Pathology. Hand Clin 2022;38(02): 183-197. Doi: 10.1016/j.hcl.2021.11.002 Link DOI
Newton A, Talwalkar S. Arthroplasty in thumb trapeziometacarpal (CMC joint) osteoarthritis: An alternative to excision arthroplasty. J Orthop 2022;35:134-139. Doi: 10.1016/j.jor.2022.11.011 Link DOI
Hozack BA, Fram B, Ilyas AM, Rivlin M, Liss FE, Jones CM. Optimal Position of the Suture Button Suspensionplasty (TightRope) for Thumb Basal Joint Arthritis. Hand (N Y) 2022;17(01):79-84. Doi: 10.1177/1558944720906551 Link DOI
Heyworth BE, Lee JH, Kim PD, Lipton CB, Strauch RJ, Rosenwasser MP. Hylan versus corticosteroid versus placebo for treatment of basal joint arthritis: a prospective, randomized, double-blinded clinical trial. J Hand Surg Am 2008;33(01):40-48. Doi: 10.1016/j.jhsa.2007.10.009 Link DOI
Esteban Lopez LMJ, Hoogendam L, Vermeulen GM, et al; The Hand-Wrist Study Group. Long-Term Outcomes of Nonsurgical Treatment of Thumb Carpometacarpal Osteoarthritis: A Cohort Study. J Bone Joint Surg Am 2023;105(23):1837-1845. Doi: 10.2106/JBJS.22.01116 Link DOI
Moher D, Hopewell S, Schulz KF, et al. CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. BMJ 2010;340:c869. Doi: 10.1136/bmj.c869 Link DOI
Duerinckx J, Verstreken F. Total joint replacement for osteoarthritis of the carpometacarpal joint of the thumb: why and how? EFORT Open Rev 2022;7(06):349-355. Doi: 10.1530/EOR-22-0027 Link DOI
Hustedt JW, Deeyor ST, Hui CH, Vohra A, Llanes AC, Silvestri BL. A Prospective Clinical Trial Comparing Denervation With Suspension Arthroplasty for Treatment of Carpometacarpal Arthritis of the Thumb. J Hand Surg Am 2023;48(04):348-353. Doi: 10.1016/j.jhsa.2022.11.021 Link DOI
Aita MA, Rodrigues FL, Alves KHCR, Oliveira RKd, Ruggiero GM, Rodrigues LMR. Bridging versus Nonbridging Dynamic External Fixation of Unstable Distal Radius Fractures in the Elderly with Polytrauma: A Randomized Study. J Wrist Surg 2019;8(05): 408-415. Doi: 10.1055/s-0039-1692480 Link DOI
Eaton RG, Glickel SZ. Trapeziometacarpal osteoarthritis. Staging as a rationale for treatment. Hand Clin 1987;3(04):455-471
Maeda A, Ikeguchi R, Noguchi T, et al. Clinical Results of Arthroscopic Partial Trapeziectomy With Suture-Button Suspensionplasty for Thumb Carpometacarpal Arthritis. Hand (N Y) 2023; 18(05):740-745. Doi: 10.1177/15589447221075663 Link DOI
Fess E. Grip strength. In: Casanova JS, editor. Clinical assessment recommendations. 2nd ed. Chicago: American Society of Hand Therapists; 1992:41-55
Al Snih S, Markides KS, Ottenbacher KJ, Raji MA. Hand grip strength and incident ADL disability in elderly Mexican Americans over a seven-year period. Aging Clin Exp Res 2004;16(06): 481-486. Doi: 10.1007/BF03327406 Link DOI
Petersen P, Petrick M, Connor H, Conklin D. Grip strength and hand dominance: challenging the 10% rule. Am J Occup Ther 1989;43(07):444-447. Doi: 10.5014/ajot.43.7.444 Link DOI
Gummesson C, Ward MM, Atroshi I. The shortened disabilities of the arm, shoulder and hand questionnaire (QuickDASH): validity and reliability based on responses within the full-length DASH. BMC Musculoskelet Disord 2006;7:44. Doi: 10.1186/1471-2474-7-44 Link DOI
Orfale AG, Araújo PMP, Ferraz MB, Natour J. Translation into Brazilian Portuguese, cultural adaptation and evaluation of the reliability of the Disabilities of the Arm, Shoulder and Hand Questionnaire. Braz J Med Biol Res 2005;38(02):293-302. Doi: 10.1590/s0100-879x2005000200018 Link DOI
Bricout M, Rezzouk J. Complications and failures of the trapeziometacarpal Maia® prosthesis: A series of 156 cases. Hand Surg Rehabil 2016;35(03):190-198. Doi: 10.1016/j.hansur.2016.02.005 Link DOI
Luria S, Waitayawinyu T, Nemechek N, Huber P, Tencer AF, Trumble TE. Biomechanic analysis of trapeziectomy, ligament reconstruction with tendon interposition, and tie-in trapezium implant arthroplasty for thumb carpometacarpal arthritis: a cadaver study. J Hand Surg Am 2007;32(05):697-706. Doi: 10.1016/j.jhsa.2007.02.025 Link DOI
Farkash U, Sakhnini M, Dreyfuss D, Tordjman D, Rotem G, Luria S. Failure Rate and Early Complications of Thumb Carpometacarpal Joint Replacement-A Multicenter Retrospective Study of Two Modern Implant Designs. J Clin Med 2023;13(01):121. Doi: 10.3390/jcm13010121 Link DOI
Aita MA, Alves RS, Longuino LF, Ferreira CH, Ikeuti DH, Rodrigues LM. Measurement of quality of life among patient undergoing arthroplasty of the thumb to treat CMC arthritis. Rev Bras Ortop 2016;51(04):431-436. Doi: 10.1016/j.rboe.2016.06.003 Link DOI
Toffoli A, Degeorge B, Cloquell Y, Teissier P, Teissier J. MAÏA Trapeziometacarpal Joint Arthroplasty: Clinical and Radiological Outcomes of 76 Patients With More Than 10 Years of Follow-Up. J Hand Surg Am 2024;49(09):846-856. Doi: 10.1016/j.jhsa.2024.03.019 Link DOI